NMR relaxation and self-diffusion in aqueous micellar gels of pluronic F-127
نویسندگان
چکیده
منابع مشابه
Applications of thermo-reversible pluronic F-127 gels in pharmaceutical formulations.
It is, sometimes, desirable to maintain a constant plasma drug concentration within the therapeutically effective concentration range. The use of high viscosity hydromiscible vehicles such as hydrophilic gels, is one of various approaches for controlled drug delivery, and represents an important area of pharmaceutical research and development. Of these systems, Pluronic F-127 (PF-127) provides ...
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The present study investigated the release profiles of insulin from Pluronic F-127 (PF-127) gel containing unsaturated fatty acids such as oleic acid (18:1), eicosapentaenoic acid (20:5) or docosahexaenoic acid (22:6) and the hypoglycemic effect of insulin following the buccal administration of the gel formulations in normal rats. Insulin release from the gels decreased in the presence of unsat...
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ژورنال
عنوان ژورنال: Journal of Molecular Liquids
سال: 2020
ISSN: 0167-7322
DOI: 10.1016/j.molliq.2020.112898